Consensus standards
Establish shared expectations for organoids, microphysiological systems, and body-on-a-chip technologies.
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Standards Development Organization
MOSSDO
The Microphysiological and Organoid Systems Standards Development Organization establishes consensus-based standards for organoids, microphysiological systems, and body-on-a-chip technologies.
Standards Development Organization
About MOSSDO
The Microphysiological and Organoid Systems Standards Development Organization (MOSSDO) is a federally funded multi-stakeholder initiative focused specifically on establishing consensus-based standards for organoids, microphysiological systems (MPS), and body-on-a-chip technologies. MOSSDO develops frameworks for reproducibility, validation, and interoperability, enabling these platforms to be more reliably adopted across research, regulatory, and translational settings. In coordination with enabling ecosystem efforts such as PhysioVerse, MOSSDO provides the standards foundation that supports data integration, comparability, and broader field-wide adoption.
MOSSDO gives the organoid and MPS ecosystem a focused standards home. Its work helps align terminology, validation expectations, quality practices, and data comparability across the communities that develop, evaluate, and translate advanced in vitro systems.
Standards foundation
What MOSSDO supports
MOSSDO focuses on the practical standards infrastructure needed to make advanced in vitro systems more reproducible, comparable, and useful across research, regulatory, and translational settings.
Reproducibility
Support frameworks that make experimental systems easier to compare, repeat, and evaluate across settings.
Validation
Advance practices that help human-relevant platforms move toward reliable adoption in research, regulatory, and translational settings.
Interoperability
Strengthen the standards foundation needed for data integration, comparability, and broader field-wide adoption.
Ecosystem alignment
MOSSDO and PhysioVerse
PhysioVerse connects datasets, tools, workflows, training, and standards exchange for organoids, body-on-chip systems, tissue chips, and related microphysiological systems. MOSSDO provides a complementary standards foundation that helps those resources become easier to align and compare.
This connection is especially important as the field moves toward shared practices for validation, interoperability, quality control, and translational readiness.