Open-source ecosystem for in vitro and microphysiological systems
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Save the DateDecember 1-2, 2026Charlotte, North Carolina12th Annual Regenerative Manufacturing Innovation Consortium (RegMIC) Meeting: A Roadmap for Tissue Organoids and Body-on-a-Chip Manufacturing Standards
About MOSSDOAbout RegMICAbout the RegMIC 2026 meeting
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Open-source resources

Open-Source Resources for PhysioVerse

PhysioVerse maintains reusable resources that help contributors, users, curators, and developers apply shared practices in practical workflows.

What is maintained

Resources that make shared practices usable

Open-source resources should help people do real work: prepare data, describe systems, validate records, review submissions, search datasets, and reuse approved resources.

Resource types

  • Metadata templates and descriptor guidance
  • Example dataset records and manifests
  • Validation resources and review checklists
  • Documentation for contributors, users, curators, and developers
  • Workflow components that support submission, review, discovery, and reuse

Contribution pathways

Ways to contribute

Contributions can be scientific, technical, documentary, or curatorial. The goal is to improve resources that are maintained and reused by the community.

Improve documentation

Clarify guidance, examples, and onboarding materials.

Contribute templates

Help refine metadata templates, descriptor examples, or sample record formats.

Build tools

Contribute schemas, validators, catalog utilities, or workflow components.

Review examples

Test resources against realistic submissions and identify gaps.

Maintenance

Open resources need review and release practices

Resources should be versioned, documented, tested against examples, and updated when workflows or community needs change. This keeps the ecosystem useful without making resources rigid or obsolete.

Maintenance practices

  • Documented changes and release notes
  • Review of templates and examples
  • Testing against representative submissions
  • Clear contribution and issue pathways

Contribute

Help maintain tools, templates, and documentation

Developers, curators, users, and contributors can help improve open resources.

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Standards and manufacturing partners

MOSSDO and RegMIC

Connect with the organizations advancing consensus standards, validation, and regenerative manufacturing across the PhysioVerse ecosystem.

About MOSSDO

The Microphysiological and Organoid Systems Standards Development Organization (MOSSDO) is a federally funded multi-stakeholder initiative focused specifically on establishing consensus-based standards for organoids, microphysiological systems (MPS), and body-on-a-chip technologies. MOSSDO develops frameworks for reproducibility, validation, and interoperability, enabling these platforms to be more reliably adopted across research, regulatory, and translational settings. In coordination with enabling ecosystem efforts such as PhysioVerse, MOSSDO provides the standards foundation that supports data integration, comparability, and broader field-wide adoption.

About RegMIC

The Regenerative Manufacturing Innovation Consortium (RegMIC), founded in 2014, is a national initiative that brings together stakeholders from industry, academia, and government to advance the manufacturing, scale-up, and commercialization of regenerative technologies. Through cross-sector collaboration, RegMIC addresses key challenges in translation, including process development, regulatory alignment, and the establishment of best practices across cell, tissue, and advanced in vitro systems.